Molecular monitoring of residual disease in chronic myelogenous leukemia patients after therapy

R Haas, R Kronenwett, G Sczakiel, A Hochhaus… - … and Molecular Therapy, 1998 - Springer
… reduced considerably if patients are monitored by molecular … , or competitive reverse
transcriptase polymerase chain reaction (… trial of interferon-alpha n 1 for chronic myeloid

Molecular monitoring of chronic myeloid leukemia

T Hughes, S Branford - Seminars in hematology, 2003 - Elsevier
… and lower progression rates than interferon-alpha. However, … (FISH) and qualitative
polymerase chain reaction (PCR) have … The level of BCR-ABL measured by competitive Q-PCR is …

Monitoring of remission status by fluorescence in situ hybridisation in chronic myeloid leukaemia patients treated with interferon-alpha.

HC Duba, S Peter, W Hilbe… - International …, 1999 - spandidos-publications.com
… be efficient in monitoring the percentage of Ph cells in patients … survival in chronic myelogenous
leukemia after cyto genetic … therapy by competitive polymerase chain reaction. Blood 87: …

Molecular monitoring of response to imatinib (Glivec®) in CML patients pretreated with interferon alpha. Low levels of residual disease are associated with continuous …

P Paschka, MC Müller, K Merx, S Kreil, C Schoch… - Leukemia, 2003 - nature.com
… of individual patients to treatment or to evaluate the efficacy of a particular … in chronic
myelogenous leukemia patients on interferon-α therapy by competitive polymerase chain reaction. …

[HTML][HTML] Monitoring treatment of chronic myeloid leukemia

M Baccarani, F Pane, G Saglio - Haematologica, 2008 - haematologica.org
polymerase chain reaction (RT-PCR) in the follow-up of CML … and to monitor the
response.27,28 However, the competitive … with high-quality performance characteristics will …

Competitive polymerase chain reaction as a method to detect the amplification of bcr-abl gene of chronic myeloid leukemia

F Campanini, MA Santucci, L Pattachini… - …, 2001 - haematologica.org
… their resistance to interferon-alpha or tyrosine kinase inhibitors. … in liquid culture or plating
efficiency in semisolid culture medium (… monitoring of residual disease in chronic myelogenous

Monitoring of minimal residual disease in chronic myeloid leukemia

S Faderl, A Hochhaus… - Hematology/Oncology …, 2004 - hemonc.theclinics.com
… ) a shift from using qualitative polymerase chain reaction (PCR) … Competitive polymerase
chain reaction to estimate the … after interferon-alpha therapy for chronic myelogenous leukemia: …

Monitoring chronic myeloid leukemia patients responding to treatment with tyrosine kinase inhibitors by real-time quantitative polymerase chain reaction

MR Antolic, R Zadro, D Sertić, B Labar - Biochemia …, 2009 - biochemia-medica.com
… was to evaluate the efficacy of a treatment protocol and to … patients were pretreated with
busulfan or interferon-alpha, … A hypothetical mechanism could be competition with IM for a …

A guide to the use of interferon-alpha in the management of chronic myelogenous leukaemia

J Cortes, S O'Brien - BioDrugs, 2000 - Springer
Patients should be monitored closely with cytogenetic and possibly other analyses such as
fluorescent in situ hybridisation (FISH) and polymerase chain reaction (… Although the efficacy

Practical monitoring of chronic myelogenous leukemia: when to change treatment

G Saglio, C Fava - Journal of the National Comprehensive Cancer …, 2012 - jnccn.org
… real-time quantitative polymerase chain reaction (RQ-PCR) … , whose efficacy as second-line
therapy in patients with imatinib-… of any products discussed in this article or their competitors. …